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<正>缺血性脑血管疾病是全球范围内导致患者残疾和死亡的主要原因[1],脑缺血后可以诱发内源性的神经发生,是机体应对缺血性损伤的一......
第一部分 视黄醇脱氢酶13(Rdh13)在四氯化碳诱导的小鼠急性肝损伤及修复过程中的作用和机制研究具有相似序列和功能的短链脱氢酶/还......
目的 探讨在胚胎发育关键期注射丙戊酸钠(VPA)对胎鼠大脑皮质神经元增殖与形态的影响.方法 孕E12.5 ICR小鼠分别腹腔注射VPA 350 m......
目的:研究成年大鼠急性脊髓损伤后,脊髓内源性神经干细胞(endogenous neural stem cells,ENSCs)分化和替换的过程,并观察脊髓损伤后......
In this study,we exposed adult aged rats to a chronic variable stress model and compare astroglial changes as a function......
Introduction In recent years, people have found that neural stem cells still exist in human and animals after the develo......
目的:临床常用吸入性麻醉药的神经毒性受到广泛关注。一些动物研究表明,七氟烷对新生鼠有一定的中枢神经毒性,可引起认知功能下降。......
Backgroud: Ginsenoside Rd(GRd) is a bioactive constituent of the herb ginseng that has been reported to stimulate endoge......
目的 观察P55PIK的N端的24个氨基酸抑制甲状腺癌细胞增殖的作用.方法 构建含有P55PIK-N端24个氨基酸的腺病毒载体Ad-N24-p55PIK-GF......
OBJECTIVE Recent studies have shown that hepsin, a type of transmembrane serine protease, is highly upregulated in prost......
急性髓性白血病HB-1细胞系是由辐射处理的CBA/N小鼠脾脏细胞克隆并建立起来的。静脉注射HB-1细胞到正常CBA/N小鼠体内会诱发急性髓......
<正> Since Latt reported his 5-bromodeoxyuridine (BrdU)-labelling plus 33258 Hoechststaining procedure for the detection......
过去曾报导过若干人类染色体具有遗传性脆性位点,其中大多数位点要在缺乏叶酸的培养基中才能得到最大的表达。也有人曾报导过仅在......
This study investigated the effects of progesterone(P4) on the production and survival of neurons in the hippocampal den......
作者报道了两例白肤色女性患者,年龄分别为2.5和33岁。核型为45,X/46,r(X)嵌合型Ullrich-Turner氏综合征,亦有严重智力障碍,神经......
系统性红斑狼疮(SLE)是一种典型的人类自身免疫性疾病。这种病的特点是能产生DNA的抗体,染色体不稳定,DNA修复机能较弱;在这种病......
来自30例连续死产或流产的一个或多个组织的活组织检查,用于一项试验性研究,以测试原位系统的功效。组织采用胎盘、羊膜、皮肤、......
Glutamine depletion induces murine neonatal melena with increased apoptosis of the intestinal epithe
AIM:To investigate the possible biological outcome and effect of glutamine depletion in neonatal mice and rodent intesti......
N-methyl-D-aspartate receptor subtype 3A promotes apoptosis in developing mouse brain exposed to hyp
In the present study, 7 day postnatal C57/BL6 wild-type mice (hyperoxia group) and 7 day postnatal N-methyl-D-aspartate ......
目的观察乙酰胆碱(ACh)对大鼠海马齿状回颗粒细胞下层成年神经发生的作用和影响。方法通过立体定位经侧脑室药物注射建立试验动物......
Autologous transplantation of bone marrow mononuclear cells improved heart function after myocardial
AIM: To investigate whether autologous transplantation of adult stem cells could improve post-infarcted heart function.......
Collagen-GAG Scaffolds Grafted Onto Myocardial Infarcts in a Rat Model:A Delivery Vehicle for Mesenc
1 IntroductionThe objective of the present study was to investigate the response of rat myocardial scar tissue to type I......
Recentstudieshavesuggestedbenefitsofmesenchymalstemcells (MSCs)transplantationfortheregenerationofcardiactissueandfuncti......
AIM:To examine the influence of ghrelin on the regenerative potential of gastrointestinal(GI)epithelium.METHODS:Damage t......
目的:研究胰岛素分泌细胞的体外诱导方法及其对大鼠糖尿病的疗效。方法:分离培养大鼠骨髓干细胞,用尼克酰胺及肠促胰岛素类似物诱......
目的:探讨液化石油气急性中毒对小鼠海马齿状回及侧脑室室管膜下区神经发生的影响。方法:选择健康成年昆明小鼠随机分三组,分别为......
Monocyte chemotactic protein 1 increases homing of mesenchymal stem cell to injured myocardium and n
Objective:To investigate the effect of MCP-1 on mesenchymal stem cells(MSCs) homing to injured myocardium in a rat myoca......
Cardiac atrioventricular conduction improved by autologous transplantation of mesenchymal stem cells
Objective Atrioventricular block (AVB) is a common and serious arrhythmia. At present, there is no perfect method of tre......
镧离子(La3+)对NIH 3T3小鼠胚胎成纤维细胞的增殖有重要影响,但其机理尚需深入研究。在本研究中,我们运用增殖分析、周期阻滞-释放......
目的:通过标记滞留细胞(LRCs)技术检测证实异位子宫内膜干细胞的存在及其在病灶内的分布情况;初步探讨抗雌激素治疗对异位子宫内膜......
在建立成功的帕金森(PD)大鼠模型的基础上,通过细胞移植法检测骨髓间充质干细胞(BMSCs)在PD模型大鼠脑内的存活和分化情况,探讨BMS......
目的:比较成年健康小鼠脑室下区及室周器官BrdU标记细胞的数量及分布,探讨生理状态下室周器官的神经生发功能。方法:成年健康BALB/......
Erythropoietin (EPO) and granulocyte colonystimulating factor (G-CSF) are likely to play broad roles in the brain. We in......
目的:探讨异常免疫反应介导的糖尿病(DM)对大脑神经干/祖细胞(NSC/NPC)增殖的影响。方法:依据尿糖测定结果将非肥胖型糖尿病(NOD)......
人类子宫内膜中存在干细胞,其对子宫内膜的再生起着关键作用。子宫内膜干细胞位于基底层,并存在上皮、间充质和内皮细胞3种类型,它......
目的:探讨同种异体骨髓间质干细胞(BMSCs)移植联合血管内皮生长因子VEGF静脉注射对兔急性心肌梗死心功能的影响。方法:体外分离、......
Gene Expression Profiling of the Proliferative Effect of Periplocin on Mouse Cardiac Microvascular E
Objective:Periplocin is an active digitalis-like component from Cortex Periplocae,which has been widely used in the trea......
The Inhibitory Effect of Somatostatin Analogue RC-160 on the Growth of Endometrial Carcinoma Cell Li
Objective:To evaluate the inhibitory effect of somatostatin analogue RC-160 on the growth of human endometrial cancer ce......
目的 观察Hoechest33342、BrdU、DAPI对大鼠BMSCs标记情况,比较其标记效果的差异性;培养转基因绿色荧光小鼠的BMSCs,观察细胞生长......
Objective: To study the effects of PDGF-Rb antagonists imatinib on endometrial injury repairing in the mouse model. Meth......
[目的]探讨同种异体骨髓基质干细胞移植治疗股骨头坏死的可行性,并研究移植细胞的转归和缺损区新生骨的来源.[方法] 24只新西兰大......
细胞增殖是细胞在周期调控因子的作用下,通过DNA复制、RNA转录和蛋白质合成等一系列复杂反应而进行的分裂过程,是生物体生长、发育、......